Massive Bioaccumulation and Self‐Assembly of Phenazine Compounds in Live Cells

Clofazimine is an orally administered drug that massively bioaccumulates in macrophages, forming membrane‐bound intracellular structures possessing nanoscale supramolecular features. Here, a library of phenazine compounds derived from clofazimine is synthesized and tested for ability to accumulate a...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Min, Kyoung Ah, Rajeswaran, Walajapet G., Oldenbourg, Rudolf, Harris, Grant, Keswani, Rahul K., Chiang, Mason, Rzeczycki, Phillip, Talattof, Arjang, Hafeez, Mahwish, Horobin, Richard W., Larsen, Scott D., Stringer, Kathleen A., Rosania, Gus R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569013/
https://ncbi.nlm.nih.gov/pubmed/26380168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201500025
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