The Physicochemical Basis of Clofazimine-Induced Skin Pigmentation

Clofazimine is a weakly basic, FDA-approved antibiotic recommended by the World Health Organization to treat leprosy and multi-drug-resistant tuberculosis. Upon prolonged treatment, clofazimine extensively bioaccumulates and precipitates throughout the organism, forming crystal-like drug inclusions...

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Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Murashov, Mikhail D., LaLone, Vernon, Rzeczycki, Phillip M., Keswani, Rahul K., Yoon, Gi S., Sud, Sudha, Rajeswaran, Walajapet, Larsen, Scott, Stringer, Kathleen A., Rosania, Gus R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828885/
https://ncbi.nlm.nih.gov/pubmed/29042210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.09.031
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