An Expandable Mechanopharmaceutical Device (2): Drug Induced Granulomas Maximize the Cargo Sequestering Capacity of Macrophages in the Liver

PURPOSE: Drug-induced liver injuries (DILI) comprise a significant proportion of adverse drug reactions leading to hospitalizations and death. One frequent DILI is granulomatous inflammation from exposure to harmful metabolites that activate inflammatory pathways of immune cells of the liver, which...

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Publicado en:Pharm Res
Main Authors: Rzeczycki, Phillip, Yoon, Gi Sang, Keswani, Rahul K., Sud, Sudha, Baik, Jason, Murashov, Mikhail D., Bergin, Ingrid L., Stringer, Kathleen A., Rosania, Gus. R.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506721/
https://ncbi.nlm.nih.gov/pubmed/30406478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2541-z
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