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Reverse Engineering the Intracellular Self-Assembly of a Functional Mechanopharmaceutical Device

Weakly basic, poorly soluble chemical agents could be exploited as building blocks for constructing sophisticated molecular devices inside the cells of living organisms. Here, using experimental and computational approaches, we probed the relationship between the biological mechanisms mediating lyso...

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Publicado en:Sci Rep
Autores principales: Woldemichael, Tehetina, Keswani, Rahul K., Rzeczycki, Phillip M., Murashov, Mikhail D., LaLone, Vernon, Gregorka, Brian, Swanson, Joel A., Stringer, Kathleen A., Rosania, Gus R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811454/
https://ncbi.nlm.nih.gov/pubmed/29440773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21271-7
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