Activation of p38 Mitogen-Activated Protein Kinase in Gaucher’s Disease

Gaucher’s disease is caused by defects in acid β-glucosidase 1 (GBA1) and has been also proposed as an inflammatory disease. GBA1 cleaves glucosylceramide to form ceramide, an established bioactive lipid, and defects in GBA1 lead to aberrant accumulation in glucosylceramide and insufficient formatio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Kitatani, Kazuyuki, Wada, Masayuki, Perry, David, Usui, Toshinori, Sun, Ying, Obeid, Lina M., Yaegashi, Nobuo, Grabowski, Gregory A., Hannun, Yusuf A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2015
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552301/
https://ncbi.nlm.nih.gov/pubmed/26312487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136633
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