Llwytho...
Isofagomine In Vivo Effects in a Neuronopathic Gaucher Disease Mouse
The pharmacological chaperone, isofagomine (IFG), enhances acid β-glucosidase (GCase) function by altering folding, trafficking, and activity in wild-type and Gaucher disease fibroblasts. The in vivo effects of IFG on GCase activity, its substrate levels, and phenotype were evaluated using a neurono...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Public Library of Science
2011
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080394/ https://ncbi.nlm.nih.gov/pubmed/21533102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019037 |
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