Defining a Role for Acid Sphingomyelinase in the p38/Interleukin-6 Pathway

Acid sphingomyelinase (ASM) is one of the key enzymes involved in regulating the metabolism of the bioactive sphingolipid ceramide in the sphingolipid salvage pathway, yet defining signaling pathways by which ASM exerts its effects has proven difficult. Previous literature has implicated sphingolipi...

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Bibliografiska uppgifter
Huvudupphovsmän: Perry, David M., Newcomb, Benjamin, Adada, Mohamad, Wu, Bill X., Roddy, Patrick, Kitatani, Kazuyuki, Siskind, Leah, Obeid, Lina M., Hannun, Yusuf A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Lipids
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139247/
https://ncbi.nlm.nih.gov/pubmed/24951586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589648
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