Regulation of CC Ligand 5/RANTES by Acid Sphingomyelinase and Acid Ceramidase

Acid sphingomyelinase (aSMase) generates the bioactive lipid ceramide (Cer) from hydrolysis of sphingomyelin (SM). However, its precise roles in regulating specific sphingolipid-mediated biological processes remain ill defined. Interestingly, the aSMase gene gives rise to two distinct enzymes, lysos...

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Detalhes bibliográficos
Main Authors: Jenkins, Russell W., Clarke, Christopher J., Canals, Daniel, Snider, Ashley J., Gault, Christopher R., Heffernan-Stroud, Linda, Wu, Bill X., Simbari, Fabio, Roddy, Patrick, Kitatani, Kazuyuki, Obeid, Lina M., Hannun, Yusuf A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075676/
https://ncbi.nlm.nih.gov/pubmed/21335555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163378
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