Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy

Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related mortality. Despite significant advances made in the treatment of other cancers, current chemotherapies offer little survival benefit in this disease. Pancreaticoduodenectomy offers patients the possibility of a cu...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:EMBO Mol Med
Autori principali: Miller, Bryan W, Morton, Jennifer P, Pinese, Mark, Saturno, Grazia, Jamieson, Nigel B, McGhee, Ewan, Timpson, Paul, Leach, Joshua, McGarry, Lynn, Shanks, Emma, Bailey, Peter, Chang, David, Oien, Karin, Karim, Saadia, Au, Amy, Steele, Colin, Carter, Christopher Ross, McKay, Colin, Anderson, Kurt, Evans, Thomas R Jeffry, Marais, Richard, Springer, Caroline, Biankin, Andrew, Erler, Janine T, Sansom, Owen J
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2015
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551344/
https://ncbi.nlm.nih.gov/pubmed/26077591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404827
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi