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The potential for targeting extracellular LOX proteins in human malignancy

The extracellular matrix (ECM) is the physical scaffold where cells are organized into tissues and organs. The ECM may be modified during cancer to allow and promote proliferation, invasion, and metastasis. The family of lysyl oxidase (LOX) enzymes cross-links collagens and elastin and, therefore, i...

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Détails bibliographiques
Auteurs principaux: Mayorca-Guiliani, Alejandro, Erler, Janine T
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848925/
https://ncbi.nlm.nih.gov/pubmed/24348049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S38110
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