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The potential for targeting extracellular LOX proteins in human malignancy
The extracellular matrix (ECM) is the physical scaffold where cells are organized into tissues and organs. The ECM may be modified during cancer to allow and promote proliferation, invasion, and metastasis. The family of lysyl oxidase (LOX) enzymes cross-links collagens and elastin and, therefore, i...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848925/ https://ncbi.nlm.nih.gov/pubmed/24348049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S38110 |
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