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Interplay Between LOX Enzymes and Integrins in the Tumor Microenvironment

Members of the lysyl oxidase (LOX) family are secreted copper-dependent amine oxidases that catalyze the covalent crosslinking of collagens and elastin in the extracellular matrix (ECM), an essential process for the structural integrity of all tissues. LOX enzymes can also remodel the tumor microenv...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Amendola, Pier Giorgio, Reuten, Raphael, Erler, Janine Terra
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562985/
https://ncbi.nlm.nih.gov/pubmed/31130685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050729
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