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Interplay Between LOX Enzymes and Integrins in the Tumor Microenvironment

Members of the lysyl oxidase (LOX) family are secreted copper-dependent amine oxidases that catalyze the covalent crosslinking of collagens and elastin in the extracellular matrix (ECM), an essential process for the structural integrity of all tissues. LOX enzymes can also remodel the tumor microenv...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Amendola, Pier Giorgio, Reuten, Raphael, Erler, Janine Terra
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562985/
https://ncbi.nlm.nih.gov/pubmed/31130685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050729
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