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Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy

Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related mortality. Despite significant advances made in the treatment of other cancers, current chemotherapies offer little survival benefit in this disease. Pancreaticoduodenectomy offers patients the possibility of a cu...

詳細記述

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書誌詳細
出版年:EMBO Mol Med
主要な著者: Miller, Bryan W, Morton, Jennifer P, Pinese, Mark, Saturno, Grazia, Jamieson, Nigel B, McGhee, Ewan, Timpson, Paul, Leach, Joshua, McGarry, Lynn, Shanks, Emma, Bailey, Peter, Chang, David, Oien, Karin, Karim, Saadia, Au, Amy, Steele, Colin, Carter, Christopher Ross, McKay, Colin, Anderson, Kurt, Evans, Thomas R Jeffry, Marais, Richard, Springer, Caroline, Biankin, Andrew, Erler, Janine T, Sansom, Owen J
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Ltd 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551344/
https://ncbi.nlm.nih.gov/pubmed/26077591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404827
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