Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression

Transcriptional regulators are recurrently altered through translocations, deletions, or aberrant expression in acute myeloid leukemia (AML). Although critically important in leukemogenesis, the underlying pathogenetic mechanisms they trigger remain largely unknown. Here, we identified that Id1 (inh...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Wang, Lan, Man, Na, Sun, Xiao-Jian, Tan, Yurong, Cao, Marta Garcia, Liu, Fan, Hatlen, Megan, Xu, Haiming, Huang, Gang, Mattlin, Meredith, Mehta, Arpit, Rampersaud, Evadnie, Benezra, Robert, Nimer, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520879/
https://ncbi.nlm.nih.gov/pubmed/26084673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-635532
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