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Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression

Transcriptional regulators are recurrently altered through translocations, deletions, or aberrant expression in acute myeloid leukemia (AML). Although critically important in leukemogenesis, the underlying pathogenetic mechanisms they trigger remain largely unknown. Here, we identified that Id1 (inh...

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Bibliografski detalji
Izdano u:Blood
Glavni autori: Wang, Lan, Man, Na, Sun, Xiao-Jian, Tan, Yurong, Cao, Marta Garcia, Liu, Fan, Hatlen, Megan, Xu, Haiming, Huang, Gang, Mattlin, Meredith, Mehta, Arpit, Rampersaud, Evadnie, Benezra, Robert, Nimer, Stephen D.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520879/
https://ncbi.nlm.nih.gov/pubmed/26084673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-635532
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