Secondary cytogenetic abnormalities in core-binding factor AML harboring inv(16) vs t(8;21)

Patients with core-binding factor (CBF) acute myeloid leukemia (AML), caused by either t(8;21)(q22;q22) or inv(16)(p13q22)/t(16;16)(p13;q22), have higher complete remission rates and longer survival than patients with other subtypes of AML. However, ∼40% of patients relapse, and the literature sugge...

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Pubblicato in:Blood Adv
Autori principali: Han, Se young, Mrózek, Krzysztof, Voutsinas, Jenna, Wu, Qian, Morgan, Elizabeth A., Vestergaard, Hanne, Ohgami, Robert, Kluin, Philip M., Kristensen, Thomas Kielsgaard, Pullarkat, Sheeja, Møller, Michael Boe, Schiefer, Ana-Iris, Baughn, Linda B., Kim, Young, Czuchlewski, David, Hilberink, Jacobien R., Horny, Hans-Peter, George, Tracy I., Dolan, Michelle, Ku, Nam K., Arana Yi, Cecilia, Pullarkat, Vinod, Kohlschmidt, Jessica, Salhotra, Amandeep, Soma, Lori, Bloomfield, Clara D., Chen, Dong, Sperr, Wolfgang R., Marcucci, Guido, Cho, Christina, Akin, Cem, Gotlib, Jason, Broesby-Olsen, Sigurd, Larson, Melissa, Linden, Michael A., Deeg, H. Joachim, Hoermann, Gregor, Perales, Miguel-Angel, Hornick, Jason L., Litzow, Mark R., Nakamura, Ryotaro, Weisdorf, Daniel, Borthakur, Gautam, Huls, Gerwin, Valent, Peter, Ustun, Celalettin, Yeung, Cecilia C. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2021
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152510/
https://ncbi.nlm.nih.gov/pubmed/34003250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003605
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