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Negative effects of GM-CSF signaling in a murine model of t(8;21)–induced leukemia
The t(8;21)(q22;q22) is common in adult acute myeloid leukemia (AML). The RUNX1-ETO fusion protein that is expressed by this translocation is poorly leukemogenic and requires additional mutations for transformation. Loss of sex chromosome (LOS) is frequently observed in t(8;21) AML. In the present s...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321875/ https://ncbi.nlm.nih.gov/pubmed/22223820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-350694 |
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