Spontaneous Aortic Regurgitation and Valvular Cardiomyopathy in Mice

OBJECTIVE: We studied the mechanistic links between fibrocalcific changes in the aortic valve and aortic valve function in mice homozygous for a hypomorphic epidermal growth factor receptor mutation (Wave mice). We also studied myocardial responses to aortic valve dysfunction in Wave mice. APPROACH...

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發表在:Arterioscler Thromb Vasc Biol
Main Authors: Hajj, Georges P., Chu, Yi, Lund, Donald D., Magida, Jason A., Funk, Nathan D., Brooks, Robert M., Baumbach, Gary L., Zimmerman, Kathy A., Davis, Melissa K., El Accaoui, Ramzi N., Hameed, Tariq, Doshi, Hardik, Chen, BiYi, Leinwand, Leslie A., Song, Long-Sheng, Heistad, Donald D., Weiss, Robert M.
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482792/
https://ncbi.nlm.nih.gov/pubmed/25997932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305729
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