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Pioglitazone Attenuates Valvular Calcification Induced by Hypercholesterolemia
OBJECTIVE: Development of calcific aortic valve stenosis (CAVS) involves multiple signaling pathways, which may be modulated by peroxisome proliferator-activated receptor-gamma (PPARγ). This study tested the hypothesis that pioglitazone, a ligand for PPARγ, inhibits calcification of the aortic valve...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3573264/ https://ncbi.nlm.nih.gov/pubmed/23288158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300794 |
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