Spontaneous Aortic Regurgitation and Valvular Cardiomyopathy in Mice

OBJECTIVE: We studied the mechanistic links between fibrocalcific changes in the aortic valve and aortic valve function in mice homozygous for a hypomorphic epidermal growth factor receptor mutation (Wave mice). We also studied myocardial responses to aortic valve dysfunction in Wave mice. APPROACH...

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Publicado en:Arterioscler Thromb Vasc Biol
Main Authors: Hajj, Georges P., Chu, Yi, Lund, Donald D., Magida, Jason A., Funk, Nathan D., Brooks, Robert M., Baumbach, Gary L., Zimmerman, Kathy A., Davis, Melissa K., El Accaoui, Ramzi N., Hameed, Tariq, Doshi, Hardik, Chen, BiYi, Leinwand, Leslie A., Song, Long-Sheng, Heistad, Donald D., Weiss, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482792/
https://ncbi.nlm.nih.gov/pubmed/25997932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305729
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