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Discovery of an Experimental Model of Unicuspid Aortic Valve
BACKGROUND: The epithelial growth factor receptor family of tyrosine kinases modulates embryonic formation of semilunar valves. We hypothesized that mice heterozygous for a dominant loss‐of‐function mutation in epithelial growth factor receptor, which are Egfr (Vel/+) mice, would develop anomalous a...
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| Publicado no: | J Am Heart Assoc |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6064885/ https://ncbi.nlm.nih.gov/pubmed/29960994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006908 |
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