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Evidence for active regulation of pro-osteogenic signaling in advanced aortic valve disease

OBJECTIVE: This study tested the hypothesis that valvular calcium deposition, pro-osteogenic signaling, and function can be altered in mice with advanced aortic valve disease. METHODS/RESULTS: “Reversa” mice were placed on a Western-type diet for 12 months and screened for the presence of aortic val...

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Detalhes bibliográficos
Main Authors: Miller, Jordan D., Weiss, Robert M., Serrano, Kristine M., Castaneda, Lauren E., Brooks, Robert M., Zimmerman, Kathy, Heistad, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996870/
https://ncbi.nlm.nih.gov/pubmed/20864669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.211029
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