Fibrotic Aortic Valve Stenosis in Hypercholesterolemic/Hypertensive Mice

OBJECTIVE: Hypercholesterolemia (HC) and hypertension (HT) are associated with aortic valve stenosis (AVS) in humans. We have examined aortic valve function, structure, and gene expression in HC/HT mice. APPROACH AND RESULTS: Control, hypertensive (HT), hypercholesterolemic (Apoe(−/−)) (HC), and HC/...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Chu, Yi, Lund, Donald D., Doshi, Hardik, Keen, Henry L., Knudtson, Kevin L., Funk, Nathan D., Shao, Jian Q., Cheng, Justine, Hajj, Georges P., Zimmerman, Kathy A., Davis, Melissa K., Brooks, Robert M., Chapleau, Mark W., Sigmund, Curt D., Weiss, Robert M., Heistad, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767592/
https://ncbi.nlm.nih.gov/pubmed/26769049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306912
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