Aortic valve sclerosis in mice deficient in endothelial nitric oxide synthase

Risk factors for fibrocalcific aortic valve disease (FCAVD) are associated with systemic decreases in bioavailability of endothelium-derived nitric oxide (EDNO). In patients with bicuspid aortic valve (BAV), vascular expression of endothelial nitric oxide synthase (eNOS) is decreased, and eNOS(−/−)...

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Autors principals: El Accaoui, Ramzi N., Gould, Sarah T., Hajj, Georges P., Chu, Yi, Davis, Melissa K., Kraft, Diane C., Lund, Donald D., Brooks, Robert M., Doshi, Hardik, Zimmerman, Kathy A., Kutschke, William, Anseth, Kristi S., Heistad, Donald D., Weiss, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
Matèries:
Vascular Biology and Microcirculation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010666/
https://ncbi.nlm.nih.gov/pubmed/24610917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00392.2013
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