Aortic valve sclerosis in mice deficient in endothelial nitric oxide synthase

Risk factors for fibrocalcific aortic valve disease (FCAVD) are associated with systemic decreases in bioavailability of endothelium-derived nitric oxide (EDNO). In patients with bicuspid aortic valve (BAV), vascular expression of endothelial nitric oxide synthase (eNOS) is decreased, and eNOS(−/−)...

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Detalhes bibliográficos
Main Authors: El Accaoui, Ramzi N., Gould, Sarah T., Hajj, Georges P., Chu, Yi, Davis, Melissa K., Kraft, Diane C., Lund, Donald D., Brooks, Robert M., Doshi, Hardik, Zimmerman, Kathy A., Kutschke, William, Anseth, Kristi S., Heistad, Donald D., Weiss, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010666/
https://ncbi.nlm.nih.gov/pubmed/24610917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00392.2013
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