Aortic valve sclerosis in mice deficient in endothelial nitric oxide synthase

Risk factors for fibrocalcific aortic valve disease (FCAVD) are associated with systemic decreases in bioavailability of endothelium-derived nitric oxide (EDNO). In patients with bicuspid aortic valve (BAV), vascular expression of endothelial nitric oxide synthase (eNOS) is decreased, and eNOS(−/−)...

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Detalles Bibliográficos
Main Authors: El Accaoui, Ramzi N., Gould, Sarah T., Hajj, Georges P., Chu, Yi, Davis, Melissa K., Kraft, Diane C., Lund, Donald D., Brooks, Robert M., Doshi, Hardik, Zimmerman, Kathy A., Kutschke, William, Anseth, Kristi S., Heistad, Donald D., Weiss, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
Assuntos:
Vascular Biology and Microcirculation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010666/
https://ncbi.nlm.nih.gov/pubmed/24610917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00392.2013
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