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Spontaneous Aortic Regurgitation and Valvular Cardiomyopathy in Mice

OBJECTIVE: We studied the mechanistic links between fibrocalcific changes in the aortic valve and aortic valve function in mice homozygous for a hypomorphic epidermal growth factor receptor mutation (Wave mice). We also studied myocardial responses to aortic valve dysfunction in Wave mice. APPROACH...

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Hajj, Georges P., Chu, Yi, Lund, Donald D., Magida, Jason A., Funk, Nathan D., Brooks, Robert M., Baumbach, Gary L., Zimmerman, Kathy A., Davis, Melissa K., El Accaoui, Ramzi N., Hameed, Tariq, Doshi, Hardik, Chen, BiYi, Leinwand, Leslie A., Song, Long-Sheng, Heistad, Donald D., Weiss, Robert M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482792/
https://ncbi.nlm.nih.gov/pubmed/25997932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305729
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