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Precision cancer mouse models through genome editing with CRISPR-Cas9
The cancer genome is highly complex, with hundreds of point mutations, translocations, and chromosome gains and losses per tumor. To understand the effects of these alterations, precise models are needed. Traditional approaches to the construction of mouse models are time-consuming and laborious, re...
Kaydedildi:
| Yayımlandı: | Genome Med |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BioMed Central
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460969/ https://ncbi.nlm.nih.gov/pubmed/26060510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0178-7 |
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