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Editing the Mouse Genome Using the CRISPR-Cas9 System

The ability to modify the murine genome was perhaps one of the most important developments in modern biology. However, traditional methods of genomic engineering are costly and relatively clumsy in their approach. The utilization of programmable nucleases, which include zinc finger nucleases (ZFNs)...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Protoc
Main Authors: Williams, Adam, Henao-Mejia, Jorge, Flavell, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898480/
https://ncbi.nlm.nih.gov/pubmed/26832693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.top087536
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