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Editing the Mouse Genome Using the CRISPR-Cas9 System

The ability to modify the murine genome was perhaps one of the most important developments in modern biology. However, traditional methods of genomic engineering are costly and relatively clumsy in their approach. The utilization of programmable nucleases, which include zinc finger nucleases (ZFNs)...

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Bibliografische gegevens
Gepubliceerd in:Cold Spring Harb Protoc
Hoofdauteurs: Williams, Adam, Henao-Mejia, Jorge, Flavell, Richard A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898480/
https://ncbi.nlm.nih.gov/pubmed/26832693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.top087536
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