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Generation of Genetically Modified Mice using the CRISPR-Cas9 Genome-Editing System
Genetically modified mice are extremely valuable tools for studying gene function and human diseases. Although the generation of mice with specific genetic modifications through traditional methods using homologous recombination in embryonic stem (ES) has been invaluable in the last two decades, it...
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| Publicado no: | Cold Spring Harb Protoc |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905559/ https://ncbi.nlm.nih.gov/pubmed/26832688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.prot090704 |
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