Detailed Phenotypic and Molecular Analyses of Genetically Modified Mice Generated by CRISPR-Cas9-Mediated Editing

The bacterial CRISPR-Cas9 system has been adapted for use as a genome editing tool. While several recent reports have indicated that successful genome editing of mice can be achieved, detailed phenotypic and molecular analyses of the mutant animals are limited. Following pronuclear micro-injection o...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Parikh, Bijal A., Beckman, Diana L., Patel, Swapneel J., White, J. Michael, Yokoyama, Wayne M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294663/
https://ncbi.nlm.nih.gov/pubmed/25587897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116484
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