Detailed Phenotypic and Molecular Analyses of Genetically Modified Mice Generated by CRISPR-Cas9-Mediated Editing

The bacterial CRISPR-Cas9 system has been adapted for use as a genome editing tool. While several recent reports have indicated that successful genome editing of mice can be achieved, detailed phenotypic and molecular analyses of the mutant animals are limited. Following pronuclear micro-injection o...

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Spremljeno u:
Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Parikh, Bijal A., Beckman, Diana L., Patel, Swapneel J., White, J. Michael, Yokoyama, Wayne M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294663/
https://ncbi.nlm.nih.gov/pubmed/25587897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116484
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