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Detailed Phenotypic and Molecular Analyses of Genetically Modified Mice Generated by CRISPR-Cas9-Mediated Editing

The bacterial CRISPR-Cas9 system has been adapted for use as a genome editing tool. While several recent reports have indicated that successful genome editing of mice can be achieved, detailed phenotypic and molecular analyses of the mutant animals are limited. Following pronuclear micro-injection o...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Parikh, Bijal A., Beckman, Diana L., Patel, Swapneel J., White, J. Michael, Yokoyama, Wayne M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294663/
https://ncbi.nlm.nih.gov/pubmed/25587897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116484
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