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CRISPR-Cas9 DNA Base-Editing and Prime-Editing

Many genetic diseases and undesirable traits are due to base-pair alterations in genomic DNA. Base-editing, the newest evolution of clustered regularly interspaced short palindromic repeats (CRISPR)-Cas-based technologies, can directly install point-mutations in cellular DNA without inducing a doubl...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Kantor, Ariel, McClements, Michelle E., MacLaren, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503568/
https://ncbi.nlm.nih.gov/pubmed/32872311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176240
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