An analysis of retinal gene therapy clinical trials: successful translation will depend on successful translation

per MacLaren, Robert E
Publicat 2009

Comment: Gene Therapy for Age-related Macular Degeneration

per MacLaren, Robert E
Publicat a Lancet (2015)

Cone fusion confusion in photoreceptor transplantation

per MacLaren, Robert E.
Publicat a Stem Cell Investig (2017)

Stem cells as a therapeutic tool for the blind: biology and future prospects

per Singh, Mandeep S., MacLaren, Robert E.
Publicat 2011

Recent advances and future prospects in choroideremia

per Zinkernagel, Martin S, MacLaren, Robert E
Publicat a Clin Ophthalmol (2015)

Ocular gene therapy for choroideremia: clinical trials and future perspectives

per Xue, Kanmin, MacLaren, Robert E.
Publicat a Expert Rev Ophthalmol (2018)

Correcting visual loss by genetics and prosthetics

per Xue, Kanmin, MacLaren, Robert E.
Publicat a Curr Opin Physiol (2020)

Translating Induced Pluripotent Stem Cells from Bench to Bedside: Application to Retinal Diseases

per Cramer, Alona O., MacLaren, Robert E.
Publicat 2013


The Application of CRISPR/Cas9 for the Treatment of Retinal Diseases


per Peddle, Caroline F., MacLaren, Robert E.
Publicat a Yale J Biol Med (2017)

Comment on: ‘Sector retinitis pigmentosa caused by mutations of the RHO gene’

per Orlans, Harry O., MacLaren, Robert E.
Publicat a Eye (Lond) (2019)

Induced pluripotent stem cell therapies for retinal disease

per Comyn, Oliver, Lee, Edward, MacLaren, Robert E
Publicat 2010

Gene therapy for retinal disease

per McClements, Michelle E, MacLaren, Robert E
Publicat 2013


Adeno-associated Virus (AAV) Dual Vector Strategies for Gene Therapy Encoding Large Transgenes

per McClements, Michelle E., MacLaren, Robert E.
Publicat a Yale J Biol Med (2017)

Novel non-sense mutation in RP2 (c.843_844insT/p.Arg282fs) is associated with a severe phenotype of retinitis pigmentosa without evidence of primary retinal pigment epithelium invo...

per Horner, Faye, Wawrzynski, James, MacLaren, Robert E
Publicat a BMJ Case Rep (2019)

Gene Therapy for Choroideremia Using an Adeno-Associated Viral (AAV) Vector

per Barnard, Alun R., Groppe, Markus, MacLaren, Robert E.
Publicat a Cold Spring Harb Perspect Med (2015)

Selective Automated Perimetry Under Photopic, Mesopic, and Scotopic Conditions: Detection Mechanisms and Testing Strategies

per Simunovic, Matthew P., Moore, Anthony T., MacLaren, Robert E.
Publicat a Transl Vis Sci Technol (2016)

Gene Therapy and Stem Cell Transplantation in Retinal Disease: The New Frontier

per MacLaren, Robert E., Bennett, Jean, Schwartz, Steven D.
Publicat a Ophthalmology (2016)

Outcome Measures Used in Ocular Gene Therapy Trials: A Scoping Review of Current Practice

per Jolly, Jasleen K., Bridge, Holly, MacLaren, Robert E.
Publicat a Front Pharmacol (2019)

Monitoring progression of retinitis pigmentosa: current recommendations and recent advances

per Menghini, Moreno, Cehajic-Kapetanovic, Jasmina, MacLaren, Robert E
Publicat a Expert Opin Orphan Drugs (2020)

Risks of gene therapy should be weighed against lack of alternatives for many diseases

per MacLaren, Robert E, Ali, Robin R, Thrasher, Adrian J
Publicat 2005