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Generating Mouse Models Using CRISPR-Cas9 Mediated Genome Editing
The CRISPR-Cas9 system in bacteria and archaea has recently been exploited for genome editing in various model organisms, including mice. The CRISPR-Cas9 reagents can be delivered directly into the mouse zygote to derive a mutant animal carrying targeted genetic modifications. The major components o...
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| Publicado en: | Curr Protoc Mouse Biol |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4848752/ https://ncbi.nlm.nih.gov/pubmed/26928663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470942390.mo150178 |
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