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Redefining mouse transgenesis with CRISPR/Cas9 genome editing technology
The generation of genetically modified alleles in mice using conventional transgenesis technologies is a long and inefficient process. A new study shows that the in situ delivery of CRISPR/Cas9 reagents into pregnant mice results in a high efficiency of editing, and enables the rapid generation of b...
Tallennettuna:
| Julkaisussa: | Genome Biol |
|---|---|
| Päätekijä: | |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5831610/ https://ncbi.nlm.nih.gov/pubmed/29490686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1409-1 |
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