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CRISPR–Cas9-mediated genome editing and guide RNA design

CRISPR and CRISPR-associated (Cas) proteins, which in nature comprise the RNA-based adaptive immune system in bacteria and archaea, have emerged as particularly powerful genome editing tools owing to their unrivaled ease of use and ability to modify genomes across mammalian model systems. As such, t...

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Bibliografiske detaljer
Udgivet i:Mamm Genome
Main Authors: Wiles, Michael V., Qin, Wenning, Cheng, Albert W., Wang, Haoyi
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602062/
https://ncbi.nlm.nih.gov/pubmed/25991564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-015-9565-z
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