Optimization of genome editing through CRISPR-Cas9 engineering

CRISPR (Clustered Regularly-Interspaced Short Palindromic Repeats)-Cas9 (CRISPR associated protein 9) has rapidly become the most promising genome editing tool with great potential to revolutionize medicine. Through guidance of a 20 nucleotide RNA (gRNA), CRISPR-Cas9 finds and cuts target protospace...

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Detalhes bibliográficos
Publicado no:Bioengineered
Main Authors: Zhang, Jian-Hua, Adikaram, Poorni, Pandey, Mritunjay, Genis, Allison, Simonds, William F.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Commentary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927198/
https://ncbi.nlm.nih.gov/pubmed/27340770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2016.1189039
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