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Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity

Advances in the development of delivery, repair, and specificity strategies for the CRISPR-Cas9 genome engineering toolbox are helping researchers understand gene function with unprecedented precision and sensitivity. CRISPR-Cas9 also holds enormous therapeutic potential for the treatment of genetic...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Tycko, Josh, Myer, Vic E., Hsu, Patrick D.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976696/
https://ncbi.nlm.nih.gov/pubmed/27494557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.07.004
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