Llwytho...
Precision cancer mouse models through genome editing with CRISPR-Cas9
The cancer genome is highly complex, with hundreds of point mutations, translocations, and chromosome gains and losses per tumor. To understand the effects of these alterations, precise models are needed. Traditional approaches to the construction of mouse models are time-consuming and laborious, re...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Genome Med |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BioMed Central
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460969/ https://ncbi.nlm.nih.gov/pubmed/26060510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0178-7 |
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