Acetate is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

Glioblastomas and brain metastases are highly proliferative brain tumors with short survival times. Previously, using (13)C-NMR analysis of brain tumors resected from patients during infusion of (13)C-glucose, we demonstrated that there is robust oxidation of glucose in the citric acid cycle, yet gl...

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Detaylı Bibliyografya
Yayımlandı:Cell
Asıl Yazarlar: Mashimo, Tomoyuki, Pichumani, Kumar, Vemireddy, Vamsidhara, Hatanpaa, Kimmo J., Singh, Dinesh Kumar, Sirasanagandla, Shyam, Nannepaga, Suraj, Piccirillo, Sara G., Kovacs, Zoltan, Foong, Chan, Huang, Zhiguang, Barnett, Samuel, Mickey, Bruce E., DeBerardinis, Ralph J., Tu, Benjamin P., Maher, Elizabeth A., Bachoo, Robert M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374602/
https://ncbi.nlm.nih.gov/pubmed/25525878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.025
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