Acetate is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

Glioblastomas and brain metastases are highly proliferative brain tumors with short survival times. Previously, using (13)C-NMR analysis of brain tumors resected from patients during infusion of (13)C-glucose, we demonstrated that there is robust oxidation of glucose in the citric acid cycle, yet gl...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell
Main Authors: Mashimo, Tomoyuki, Pichumani, Kumar, Vemireddy, Vamsidhara, Hatanpaa, Kimmo J., Singh, Dinesh Kumar, Sirasanagandla, Shyam, Nannepaga, Suraj, Piccirillo, Sara G., Kovacs, Zoltan, Foong, Chan, Huang, Zhiguang, Barnett, Samuel, Mickey, Bruce E., DeBerardinis, Ralph J., Tu, Benjamin P., Maher, Elizabeth A., Bachoo, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374602/
https://ncbi.nlm.nih.gov/pubmed/25525878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.025
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares