Acetate is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

Glioblastomas and brain metastases are highly proliferative brain tumors with short survival times. Previously, using (13)C-NMR analysis of brain tumors resected from patients during infusion of (13)C-glucose, we demonstrated that there is robust oxidation of glucose in the citric acid cycle, yet gl...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell
Päätekijät: Mashimo, Tomoyuki, Pichumani, Kumar, Vemireddy, Vamsidhara, Hatanpaa, Kimmo J., Singh, Dinesh Kumar, Sirasanagandla, Shyam, Nannepaga, Suraj, Piccirillo, Sara G., Kovacs, Zoltan, Foong, Chan, Huang, Zhiguang, Barnett, Samuel, Mickey, Bruce E., DeBerardinis, Ralph J., Tu, Benjamin P., Maher, Elizabeth A., Bachoo, Robert M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374602/
https://ncbi.nlm.nih.gov/pubmed/25525878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.025
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