Acetate is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

Glioblastomas and brain metastases are highly proliferative brain tumors with short survival times. Previously, using (13)C-NMR analysis of brain tumors resected from patients during infusion of (13)C-glucose, we demonstrated that there is robust oxidation of glucose in the citric acid cycle, yet gl...

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Bibliografske podrobnosti
izdano v:Cell
Main Authors: Mashimo, Tomoyuki, Pichumani, Kumar, Vemireddy, Vamsidhara, Hatanpaa, Kimmo J., Singh, Dinesh Kumar, Sirasanagandla, Shyam, Nannepaga, Suraj, Piccirillo, Sara G., Kovacs, Zoltan, Foong, Chan, Huang, Zhiguang, Barnett, Samuel, Mickey, Bruce E., DeBerardinis, Ralph J., Tu, Benjamin P., Maher, Elizabeth A., Bachoo, Robert M.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374602/
https://ncbi.nlm.nih.gov/pubmed/25525878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.025
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