Hepatic Gluconeogenesis Influences (13)C Enrichment in Lactate in Human Brain Tumors During Metabolism of [1,2-(13)C]acetate

(13)C-enriched compounds are readily metabolized in human malignancies. Fragments of the tumor, acquired by biopsy or surgical resection, may be acid-extracted and (13)C NMR spectroscopy of metabolites such as glutamate, glutamine, 2-hydroxyglutarate, lactate and others provide a rich source of info...

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Bibliografske podrobnosti
izdano v:Neurochem Int
Main Authors: Pichumani, Kumar, Mashimo, Tomoyuki, Vemireddy, Vamsidhara, Kovacs, Zoltan, Ratnakar, James, Mickey, Bruce, Malloy, Craig R., DeBerardinis, Ralph J., Bachoo, Robert M., Maher, Elizabeth A.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951105/
https://ncbi.nlm.nih.gov/pubmed/27020407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2016.03.015
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