TMOD-22. WILD-TYPE p53 DRIVES A MESENCHYMAL PHENOTYPE AFTER TREATMENT OF PRIMARY GLIOBLASTOMA

Glioblastoma (GBM) is the most common and aggressive adult brain malignancy for which conventional surgery, radiation treatment and chemotherapy based on alkylating agent Temozolomide (TMZ) have limited benefit. Overall survival is variable but less than 10% of GBM patients survive 5 years, making i...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Li, Li, Vemireddy, Vamsidhara, Mashimo, Tomoyuki, Huntington, Paula, Mickey, Bruce, Maher, Elizabeth, Bachoo, Robert, Piccirillo, Sara GM
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691959/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1059
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