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TMOD-22. WILD-TYPE p53 DRIVES A MESENCHYMAL PHENOTYPE AFTER TREATMENT OF PRIMARY GLIOBLASTOMA

Glioblastoma (GBM) is the most common and aggressive adult brain malignancy for which conventional surgery, radiation treatment and chemotherapy based on alkylating agent Temozolomide (TMZ) have limited benefit. Overall survival is variable but less than 10% of GBM patients survive 5 years, making i...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Li, Li, Vemireddy, Vamsidhara, Mashimo, Tomoyuki, Huntington, Paula, Mickey, Bruce, Maher, Elizabeth, Bachoo, Robert, Piccirillo, Sara GM
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691959/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1059
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