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TMOD-22. MODELING SEX DIFFERENCES IN p53 GAIN-OF-FUNCTION MUTATIONS IN GLIOBLASTOMA

The tumor suppressor TP53 (p53) is the most commonly mutated gene in cancer and is one of the most frequently mutated genes in glioblastoma (GBM). The most common p53 mutations are missense mutations in the DNA binding domain that lead to the expression of full length mutant p53 protein. In addition...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Rockwell, Nathan, Warrington, Nicole, Rubin, Joshua
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216635/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1134
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