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TMOD-22. MODELING SEX DIFFERENCES IN p53 GAIN-OF-FUNCTION MUTATIONS IN GLIOBLASTOMA

The tumor suppressor TP53 (p53) is the most commonly mutated gene in cancer and is one of the most frequently mutated genes in glioblastoma (GBM). The most common p53 mutations are missense mutations in the DNA binding domain that lead to the expression of full length mutant p53 protein. In addition...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Rockwell, Nathan, Warrington, Nicole, Rubin, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216635/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1134
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