Measurement of (13)C turnover into glutamate and glutamine pools in brain tumor patients

Malignant brain tumors are known to utilize acetate as an alternate carbon source in the citric acid cycle for their bioenergetics. (13)C NMR based isotopomer analysis has been used to measure turnover of (13)C-acetate carbons into glutamate and glutamine pools in tumors. Plasma from the patients in...

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Détails bibliographiques
Publié dans:FEBS Lett
Auteurs principaux: Pichumani, Kumar, Mashimo, Tomoyuki, Vemireddy, Vamsidhara, Ijare, Omkar B., Mickey, Bruce E., Malloy, Craig R., Marin-Valencia, Isaac, Baskin, David S., Bachoo, Robert M., Maher, Elizabeth A.
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763554/
https://ncbi.nlm.nih.gov/pubmed/28963851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12867
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