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Critical Roles of Clostridium difficile Toxin B Enzymatic Activities in Pathogenesis
TcdB is one of the key virulence factors of Clostridium difficile that is responsible for causing serious and potentially fatal colitis. The toxin contains at least two enzymatic domains: an effector glucosyltransferase domain for inactivating host Rho GTPases and a cysteine protease domain for the...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Infect Immun |
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Κύριοι συγγραφείς: | , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
American Society for Microbiology
2015
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294253/ https://ncbi.nlm.nih.gov/pubmed/25404023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02316-14 |
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