Critical Roles of Clostridium difficile Toxin B Enzymatic Activities in Pathogenesis

TcdB is one of the key virulence factors of Clostridium difficile that is responsible for causing serious and potentially fatal colitis. The toxin contains at least two enzymatic domains: an effector glucosyltransferase domain for inactivating host Rho GTPases and a cysteine protease domain for the...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Li, Shan, Shi, Lianfa, Yang, Zhiyong, Zhang, Yongrong, Perez-Cordon, Gregorio, Huang, Tuxiong, Ramsey, Jeremy, Oezguen, Numan, Savidge, Tor C., Feng, Hanping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
Onderwerpen:
Molecular Pathogenesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294253/
https://ncbi.nlm.nih.gov/pubmed/25404023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02316-14
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