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Glucosyltransferase activity of Clostridium difficile Toxin B is essential for disease pathogenesis
Clostridium difficile TcdB harbors a glucosyltransferase that targets host Rho GTPases. However, the role of the enzyme activity in the induction of host intestinal disease has not been demonstrated. In this study, we established a mouse acute intestinal disease model by cecum injection of wild type...
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| Gepubliceerd in: | Gut Microbes |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615278/ https://ncbi.nlm.nih.gov/pubmed/26091306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490976.2015.1062965 |
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